N-of-1 clinical trials should be incorporated into clinical practice

J Clin Epidemiol. 2010 Dec;63(12):1283-4. doi: 10.1016/j.jclinepi.2010.05.006. Epub 2010 Aug 30.


N-of-1 clinical trials have the potential to contribute to individual patient management and to the accrual of important information about populations. Incorporating these studies into clinical practice will require creative thinking so as to maintain rigor without excessive disruption of routine care.

Publication types

  • Comment

MeSH terms

  • Clinical Trials as Topic / standards*
  • Hospital Information Systems / statistics & numerical data*
  • Humans
  • Meta-Analysis as Topic
  • Patient-Centered Care
  • Precision Medicine*
  • Research Design / standards*