Use of virtual cell in studies of cellular dynamics

Int Rev Cell Mol Biol. 2010;283:1-56. doi: 10.1016/S1937-6448(10)83001-1.


The Virtual Cell (VCell) is a unique computational environment for modeling and simulation of cell biology. It has been specifically designed to be a tool for a wide range of scientists, from experimental cell biologists to theoretical biophysicists. The models created with VCell can range from the simple, to evaluate hypotheses or to interpret experimental data, to complex multilayered models used to probe the predicted behavior of spatially resolved, highly nonlinear systems. In this chapter, we discuss modeling capabilities of VCell and demonstrate representative examples of the models published by the VCell users.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Active Transport, Cell Nucleus
  • Calcium / metabolism
  • Cell Physiological Phenomena*
  • Computer Simulation*
  • Models, Biological*
  • Signal Transduction
  • User-Computer Interface


  • Calcium