Age at onset of multiple sclerosis is correlated to use of combined oral contraceptives and childbirth before diagnosis

Per Holmqvist; Mats Hammar; Anne-Marie Landtblom; Jan Brynhildsen

doi:10.1016/j.fertnstert.2010.06.045

Age at onset of multiple sclerosis is correlated to use of combined oral contraceptives and childbirth before diagnosis

Fertil Steril. 2010 Dec;94(7):2835-7. doi: 10.1016/j.fertnstert.2010.06.045.

Authors

Per Holmqvist¹, Mats Hammar, Anne-Marie Landtblom, Jan Brynhildsen

Affiliation

¹ Division of Womens and Childrens Health, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden. per.holmqvist@lvn.se

PMID: 20807659
DOI: 10.1016/j.fertnstert.2010.06.045

Abstract

The aim of this study was to evaluate whether age of onset of multiple sclerosis is related to use of combined oral contraceptives and/or timing of childbirth. The results showed that use of combined oral contraceptives and childbirth before the first multiple sclerosis symptom was correlated to a higher mean age at the onset of the disease.

MeSH terms

Adolescent
Adult
Age Distribution
Age of Onset
Contraceptives, Oral, Combined / therapeutic use*
Female
Humans
Multiple Sclerosis / diagnosis*
Multiple Sclerosis / epidemiology*
Multiple Sclerosis / etiology
Parturition* / physiology
Pregnancy
Registries
Surveys and Questionnaires
Sweden / epidemiology
Time Factors
Young Adult

Substances

Contraceptives, Oral, Combined