Sleep-disordered breathing in Vietnam veterans with posttraumatic stress disorder

Am J Geriatr Psychiatry. 2012 Mar;20(3):199-204. doi: 10.1097/JGP.0b013e3181e446ea.


Objective: : To study the prevalence of sleep-disordered breathing (SDB) in Vietnam- era veterans.

Methods: : This was an observational study of Vietnam-era veterans using unattended, overnight polysomnography, cognitive testing, and genetic measures.

Results: : A sample of 105 Vietnam-era veterans with posttraumatic stress disorder: 69% had an Apnea Hypopnea Index >10. Their mean body mass index was 31, "obese" by Centers for Disease Control and Prevention criteria, and body mass index was significantly associated with Apnea Hypopnea Index (Spearman r = 0.41, N = 97, p < 0.0001). No significant effects of sleep-disordered breathing or apolipoprotein status were found on an extensive battery of cognitive tests.

Conclusion: : There is a relatively high prevalence of SDB in these patients which raises the question of to what degree excess cognitive loss in older PTSD patients may be due to a high prevalence of SDB.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apolipoproteins E / genetics
  • Body Mass Index
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Polysomnography
  • Prevalence
  • Sleep Apnea Syndromes / complications
  • Sleep Apnea Syndromes / epidemiology*
  • Sleep Apnea Syndromes / psychology
  • Stress Disorders, Post-Traumatic / complications*
  • Veterans / psychology*
  • Veterans / statistics & numerical data
  • Vietnam Conflict*


  • Apolipoproteins E