Bacteriophages as potential new therapeutics to replace or supplement antibiotics

Trends Biotechnol. 2010 Dec;28(12):591-5. doi: 10.1016/j.tibtech.2010.08.001. Epub 2010 Aug 31.


Over recent decades, a growing body of literature has validated the use of bacteriophages for therapy and prophylaxis in the war against drug-resistant bacteria. Today, much more is known about bacteriophages than in the 1930s when phage therapy first appeared and began to spread to many countries. With rapid dissemination of multi-drug-resistant bacterial pathogens, the interest in alternative remedies to antibiotics, including bacteriophage treatments, is gaining new ground. Based on recent experience and current results of bacteriophage applications against bacterial infections in countries where this alternative therapy is approved, many scientists and companies have come to believe that the use of phages for treating and preventing bacterial diseases will be successful.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Bacterial Infections / therapy*
  • Bacteriophages / physiology*
  • Complementary Therapies / methods*
  • Drug Resistance, Bacterial
  • Humans


  • Anti-Bacterial Agents