Goodness-of-fit tests for correlated paired binary data

Stat Methods Med Res. 2012 Aug;21(4):331-45. doi: 10.1177/0962280210381176. Epub 2010 Sep 1.

Abstract

We review a few popular statistical models for correlated binary outcomes, present maximum likelihood estimates for the model parameters, and discuss model selection issues using a variety of goodness-of-fit test statistics. We apply bootstrap strategies that are computationally efficient to evaluate the performance of goodness-of-fit statistics and observe that generally the power and the type I error rate of the goodness-of-fit statistics depend on the model under investigation. Our simulation results show that careful choice of goodness-of-fit statistics is an important issue especially when we have a small sample and the outcomes are highly correlated. Two biomedical applications are included.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Double-Blind Method
  • Humans
  • Models, Statistical*
  • Scleroderma, Systemic / therapy