Low Bone Marrow Oxygen Tension and Hypoxia-Inducible factor-1α Overexpression Characterize Patients With Multiple Myeloma: Role on the Transcriptional and Proangiogenic Profiles of CD138(+) Cells

Leukemia. 2010 Nov;24(11):1967-70. doi: 10.1038/leu.2010.193. Epub 2010 Sep 2.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone Marrow Cells / pathology
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Hypoxia-Inducible Factor 1, alpha Subunit / genetics*
  • Multiple Myeloma / genetics*
  • Multiple Myeloma / pathology
  • Neovascularization, Pathologic / genetics
  • Syndecan-1 / genetics*

Substances

  • HIF1A protein, human
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Syndecan-1