Insights into developmental muscle metabolism through the use of 31P-magnetic resonance spectroscopy: a review

Pediatr Exerc Sci. 2010 Aug;22(3):350-68. doi: 10.1123/pes.22.3.350.


(31)phosphorous-magnetic resonance spectroscopy ((31)P-MRS) has become an extremely valuable technique to investigate changes in muscle metabolism noninvasively and in vivo. The purpose of this article is to critically review how (31)P-MRS has contributed to current understanding of muscle metabolic function in healthy children and adolescents. In addition, an overview of the basic principles of (31)P-MRS and its application to the study of muscle metabolism is provided and discussed in relation to child-specific methodological concerns when using this technique.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Adolescent
  • Child
  • Energy Metabolism
  • Exercise / physiology
  • Humans
  • Hydrogen-Ion Concentration
  • Magnetic Resonance Spectroscopy / methods*
  • Muscle Development / physiology*
  • Muscle, Skeletal / growth & development
  • Muscle, Skeletal / metabolism*
  • Phosphorus


  • Phosphorus
  • Adenosine Triphosphate