Abstract
During our screening of pharmacologically active principles from Indonesian medicinal plants by a hypothermic effect the methanol-extract of Brucea javanica (L.) Merr. has been found to exhibit a lethal toxicity to mice. The toxic components were isolated and identified with bruceoside A and B and yadanzioside F. Correction of 13C-nuclear magnetic resonance assignment was also mentioned.
MeSH terms
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Animals
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Fever / chemically induced*
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Glaucarubin / analogs & derivatives*
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Glaucarubin / isolation & purification
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Glaucarubin / toxicity
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Indonesia
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Magnetic Resonance Spectroscopy
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Male
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Mice
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Plant Extracts / pharmacology
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Plant Extracts / toxicity*
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Plants, Medicinal / analysis*
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Quassins*
Substances
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Plant Extracts
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Quassins
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bruceoside A
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bruceoside B
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yadanzioside F
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Glaucarubin