Invasive aspergillosis in cystic fibrosis: a fatal case in an adolescent and review of the literature

Pediatr Infect Dis J. 2011 Feb;30(2):178-80. doi: 10.1097/INF.0b013e3181f63c90.


Invasive aspergillosis is a rare complication of cystic fibrosis. In this article, we describe a case of an adolescent with cystic fibrosis, which was well-controlled previously, colonized with Aspergillus fumigatus. The patient developed fatal disseminated aspergillosis in the absence of any preexisting risk factors after a short course of intravenous corticosteroid treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Aspergillosis / diagnosis*
  • Aspergillosis / pathology
  • Aspergillus fumigatus / isolation & purification*
  • Cystic Fibrosis / complications*
  • Fatal Outcome
  • Humans
  • Immunocompromised Host
  • Immunologic Factors / therapeutic use
  • Male


  • Adrenal Cortex Hormones
  • Immunologic Factors