For millions of people around the world, tuberculosis (TB) is a cause of significant morbidity and mortality. It continues to affect the well-being of Minnesotans as well. This article reviews one Minnesota hospital's experience withTB. Through retrospective reviews of charts at the University of Minnesota Medical Center, we found that patients who tested positive for TB were more likely to be foreign-born than U.S.-born, that foreign-born patients who tested positive for TB were younger than those who tested positive and were born in the United States, and that foreign-born patients were more likely to have extrapulmonary disease than pulmonary TB.