[Peutz-Jeghers syndrome with carcinomatous degeneration of a duodenal hamartomatous polyp]

Ann Gastroenterol Hepatol (Paris). 1990 Dec;26(7):285-8.
[Article in French]


The authors report a case of Peutz-Jeghers syndrome in a young patient revealed by a duodenal carcinoma developed in a hamartomatous polyp. The absence of adenomatous lesion a the level of duodenal tumour, and the presence of hamartomatous lesions, particularly smooth muscular fibres, contiguous to carcinomatous glands, are favorable to a degenerescence of hamartomatous polyp. The question of malignant change or of the association of digestive carcinomas is discussed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Duodenal Neoplasms / complications
  • Duodenal Neoplasms / pathology*
  • Hamartoma / complications
  • Hamartoma / pathology*
  • Humans
  • Male
  • Peutz-Jeghers Syndrome / complications
  • Peutz-Jeghers Syndrome / pathology*