Temporo-parietal junction stimulation in the treatment of depersonalization disorder

Psychiatry Res. 2011 Mar 30;186(1):138-40. doi: 10.1016/j.psychres.2010.08.022. Epub 2010 Sep 15.

Abstract

This is the first clinical trial of repetitive Transcranial Magnetic Stimulation (rTMS) in depersonalization disorder (DPD). After 3weeks of right temporo-parietal junction (TPJ) rTMS, 6/12 patients responded. Five responders received 3 more weeks of right TPJ rTMS showing 68% DPD symptoms improvement. Right TPJ rTMS was safe and effective.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cross-Over Studies
  • Deep Brain Stimulation / methods*
  • Depersonalization / therapy*
  • Female
  • Follow-Up Studies
  • Functional Laterality / physiology
  • Humans
  • Male
  • Middle Aged
  • Parietal Lobe / physiology*
  • Psychiatric Status Rating Scales
  • Temporal Lobe / physiology*
  • Treatment Outcome