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. 2010 Sep 7;8(9):e1000477.
doi: 10.1371/journal.pbio.1000477.

Arms and the Man: The Problem of Symmetric Growth

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Arms and the Man: The Problem of Symmetric Growth

Lewis Wolpert. PLoS Biol. .
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Conflict of interest statement

The author has declared that no competing interests exist.


Figure 1
Figure 1. The long bones of vertebrate limbs increase in length by growth from cartilaginous growth plates.
The growth plates are cartilaginous regions that lie between the epiphysis of the future joint and the central region of the bone, the diaphysis. In the figure, bone has already replaced cartilage in the diaphysis, and more bone is being added at the growth plates. Within the growth plates, cartilage cells multiply in the proliferative zone, then mature and undergo cell enlargement and extend the bone. They are then replaced by bone . (Image: Oxford University Press)

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