Acute central nervous system complications after pulse steroid therapy in patients with systemic lupus erythematosus

A J Wysenbeek; L Leibovici; J Zoldan

Acute central nervous system complications after pulse steroid therapy in patients with systemic lupus erythematosus

J Rheumatol. 1990 Dec;17(12):1695-6.

Authors

A J Wysenbeek¹, L Leibovici, J Zoldan

Affiliation

¹ Department of Medicine B, Beilinson Medical Center, Petah Tiqva, Israel.

PMID: 2084249

Abstract

We describe 2 patients with systemic lupus erythematosus (SLE) who developed an acute psychosis and a cerebrovascular accident after pulse methylprednisolone therapy. A literature review revealed 8 additional patients with SLE with acute central nervous system complications after pulse therapy.

Publication types

Case Reports
Review

MeSH terms

Adolescent
Adrenal Cortex Hormones / adverse effects*
Adrenal Cortex Hormones / therapeutic use
Aged
Animals
Central Nervous System / drug effects*
Cerebral Infarction / etiology
Cerebral Infarction / pathology
Female
Humans
Lupus Erythematosus, Systemic / drug therapy*
Methylprednisolone / adverse effects
Methylprednisolone / therapeutic use
Mice
Psychoses, Substance-Induced / etiology
Psychoses, Substance-Induced / pathology

Substances

Adrenal Cortex Hormones
Methylprednisolone