Abstract
The pathophysiologic role of enhanced chemosensitivity to carbon dioxide and/or hypoxia has been underscored in several cardiovascular diseases, including heart failure. In the early stages of this syndrome, the chemoreflex acts as a compensatory mechanism. Later on, however, it contributes to sustain the sympathetic activation, with detrimental effects on cardiovascular function and prognosis.
MeSH terms
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Animals
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Arrhythmias, Cardiac / mortality
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Arrhythmias, Cardiac / physiopathology
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Arrhythmias, Cardiac / therapy
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Biomedical Research
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Cardiovascular Diseases / physiopathology*
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Chemoreceptor Cells
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Cheyne-Stokes Respiration / physiopathology
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Cheyne-Stokes Respiration / therapy
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Death
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Heart Failure / diagnosis
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Heart Failure / physiopathology
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Humans
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Hypercapnia / physiopathology*
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Hypertension / physiopathology
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Hypoxia / physiopathology*
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Oxygen Consumption
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Prognosis
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Rats
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Reflex / physiology
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Respiration
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Risk Factors
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Sleep Apnea, Obstructive / physiopathology
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Sympathetic Nervous System / physiology
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Time Factors
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Yoga