Abstract
We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Carrier State / epidemiology*
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Carrier State / microbiology
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Child, Preschool
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Drug Resistance, Bacterial
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Humans
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Infant
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Microbial Sensitivity Tests
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Nasopharynx / microbiology*
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Pneumococcal Infections / epidemiology*
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Pneumococcal Infections / microbiology
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Pneumococcal Infections / prevention & control
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Romania / epidemiology
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Serotyping
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Streptococcal Vaccines / administration & dosage*
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Streptococcus pneumoniae / drug effects
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Streptococcus pneumoniae / isolation & purification*
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Vaccines, Conjugate / administration & dosage
Substances
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Anti-Bacterial Agents
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Streptococcal Vaccines
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Vaccines, Conjugate