Measuring episodic abdominal pain and disability in suspected sphincter of Oddi dysfunction

World J Gastroenterol. 2010 Sep 21;16(35):4416-21. doi: 10.3748/wjg.v16.i35.4416.


Aim: To evaluate the reliability of an instrument that measures disability arising from episodic abdominal pain in patients with suspected sphincter of Oddi dysfunction (SOD).

Methods: Although several treatments have been utilized to reduce pain and associated disability, measurement tools have not been developed to reliably track outcomes. Two pilot studies were conducted to assess test-retest reliability of a newly developed instrument, the recurrent abdominal pain intensity and disability (RAPID) instrument. The RAPID score is a 90-d summation of days where productivity for various daily activities is reduced as a result of abdominal pain episodes, and is modeled after the migraine disability assessment instrument used to measure headache-related disability. RAPID was administered by telephone on 2 consecutive occasions in 2 consenting populations with suspected SOD: a pre-sphincterotomy population (Pilot I, n = 55) and a post-sphincterotomy population (Pilot II, n = 70).

Results: The average RAPID scores for Pilots I and II were: 82 d (median: 81.5 d, SD: 64 d) and 48 d (median: 0 d, SD: 91 d), respectively. The concordance between the 2 assessments for both populations was very good: 0.81 for the pre-sphincterotomy population and 0.95 for the post-sphincterotomy population.

Conclusion: The described pilot studies suggest that RAPID is a reliable instrument for measuring disability resulting from abdominal pain in suspected SOD patients.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Abdominal Pain / etiology
  • Abdominal Pain / physiopathology*
  • Adult
  • Disability Evaluation*
  • Female
  • Humans
  • Pilot Projects
  • Sphincter of Oddi Dysfunction / complications
  • Sphincter of Oddi Dysfunction / physiopathology*
  • Surveys and Questionnaires