High-resolution spectral domain optical coherence tomography technology for the visualization of contact lens to cornea relationships

Cornea. 2010 Dec;29(12):1359-67. doi: 10.1097/ICO.0b013e3181d25ce2.


Purpose: To study the utility of high-resolution spectral domain optical coherence tomography (HR SOCT) in imaging the contact lens (CL) to cornea relationships with advanced CL designs for ecstatic corneas and corneal refractive therapy.

Methods: Copernicus HR SOCT (Optopol Technology SA, Zawiercie, Poland) was used to evaluate different lens materials and designs in situ and for the preliminary assessment of the materials and corneal response to hypoxic situations.

Results: SOCT is capable of highlighting very subtle and interesting features of the CL-cornea relationships in a wide range of applications such as in rigid gas-permeable corneal and semiscleral lenses, in corneal refractive therapy and application of CLs in ocular pathology, and in the evaluation of the physiological response of the cornea.

Conclusions: HR SOCT is a powerful tool capable of providing sharp images of the anterior ocular surface highlighting the relationship between lens and cornea with great detail. This methodology has several applications to enhance fitting modeling with modern designs for advanced CL treatments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Contact Lenses*
  • Cornea / anatomy & histology*
  • Humans
  • Keratoconus / pathology*
  • Keratoconus / therapy
  • Lipids / chemistry
  • Tears / chemistry*
  • Tomography, Optical Coherence*


  • Lipids