'Where are we now with intravenous thrombolysis for acute ischaemic stroke'?

Int J Stroke. 2010 Oct;5(5):381-2. doi: 10.1111/j.1747-4949.2010.00465.x.


The publication of the updated individual patient data meta-analysis of the larger randomised trials of intravenous rt-PA for acute ischaemic stroke has re-opened the debate about how the treatment should be used in routine practice, and what information can be expected to emerge in the next 2-3 years from the ongoing trials [the largest of which is the Third International Stroke Trial (IST-3)].

MeSH terms

  • Clinical Trials as Topic
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Infusions, Intravenous
  • Meta-Analysis as Topic
  • Stroke / drug therapy*
  • Thrombolytic Therapy / methods*
  • Tissue Plasminogen Activator / therapeutic use


  • Fibrinolytic Agents
  • Tissue Plasminogen Activator