Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor

Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8228-31. doi: 10.1002/anie.201003254.

Authors

Sergey Tcherniuk¹, Dimitrios A Skoufias, Christophe Labriere, Oliver Rath, Françoise Gueritte, Catherine Guillou, Frank Kozielski

Affiliation

¹ IBS (CEA-CNRS-UJF), 41, rue Jules Horowitz, 38027 Grenoble, France.

PMID: 20857469
DOI: 10.1002/anie.201003254

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acrylonitrile / analogs & derivatives*
Acrylonitrile / pharmacology
Aurora Kinase B
Aurora Kinases
Centromere*
Indoles / pharmacology*
Inhibitor of Apoptosis Proteins
Kinesins / antagonists & inhibitors*
Microtubule-Associated Proteins / metabolism*
Protein Serine-Threonine Kinases / metabolism*
Spindle Apparatus*
Survivin

Substances

2-(1H-indol-3-yl)-3-(pyridin-3-yl)acrylonitrile
BIRC5 protein, human
Indoles
Inhibitor of Apoptosis Proteins
KIF20A protein, human
Microtubule-Associated Proteins
Survivin
AURKB protein, human
Aurora Kinase B
Aurora Kinases
Protein Serine-Threonine Kinases
Kinesins
Acrylonitrile