Subclinical atherosclerosis: evolving role of carotid intima-media thickness

Prev Cardiol. Fall 2010;13(4):186-97. doi: 10.1111/j.1751-7141.2010.00072.x.


Cardiovascular risk factors have utility in risk prediction but have limitations in predicting individual risk. Identifying an individual's risk remains a challenge. Emerging technologies such as carotid artery ultrasonography and measures of carotid intima-media thickness (CIMT) may be useful in identifying the susceptible patient who may benefit from more aggressive preventive therapy. This screening test is noninvasive, reproducible, inexpensive, and radiation-free. Recent data have improved our understanding of the application of CIMT as a screening tool for cardiovascular disease. CIMT measurement may place an individual into a higher- or lower-risk category, allowing for appropriate institution of preventive strategies.

Publication types

  • Review

MeSH terms

  • Anticholesteremic Agents / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Azetidines / therapeutic use
  • Carotid Arteries / pathology*
  • Carotid Artery Diseases / diagnosis
  • Carotid Artery Diseases / drug therapy
  • Carotid Artery Diseases / pathology*
  • Disease Progression
  • Ezetimibe
  • Humans
  • Prognosis
  • Risk Factors
  • Tunica Intima / pathology*
  • Tunica Media / pathology*


  • Anticholesteremic Agents
  • Antihypertensive Agents
  • Azetidines
  • Ezetimibe