Representation of input structure in synaptic weights by spike-timing-dependent plasticity

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Aug;82(2 Pt 1):021912. doi: 10.1103/PhysRevE.82.021912. Epub 2010 Aug 13.

Abstract

Spike-timing-dependent plasticity (STDP) has been shown to generate a synaptic weight structure that is determined by the timing of the pre- and postsynaptic spikes at the synapse. In this paper it is shown under what conditions a neuron stimulated by several pools of delta-correlated inputs encodes this input structure in its resulting weight structure. The analysis is carried out using Poisson neurons with weight-dependent STDP. The learning dynamics induced by STDP leads to both stabilization of the input weights and competition between the weights for a broad range of learning parameters. The results demonstrate how weight-dependent STDP can generate multimodal stable asymptotic distributions of the synaptic weights.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology*
  • Adaptation, Physiological / physiology
  • Animals
  • Computer Simulation
  • Humans
  • Learning / physiology
  • Models, Neurological*
  • Nerve Net / physiology*
  • Neuronal Plasticity / physiology*
  • Neurons / physiology*
  • Synaptic Transmission / physiology*