Neuraxial anesthesia for labor and cesarean delivery in a parturient with hereditary antithrombin deficiency on recombinant human antithrombin infusion therapy

J Clin Anesth. 2010 Sep;22(6):450-3. doi: 10.1016/j.jclinane.2009.05.008.


A recombinant human antithrombin (rhAT; generic name: antithrombin Alfa) has recently been developed. A 37 year-old parturient with hereditary antithrombin deficiency, receiving rhAT infusion therapy, who successfully received an epidural catheter for analgesia and anesthesia during labor and cesarean delivery, is presented.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anesthesia, Epidural / methods*
  • Antithrombin III Deficiency / complications
  • Antithrombin III Deficiency / drug therapy*
  • Antithrombins / administration & dosage*
  • Cesarean Section / methods
  • Female
  • Humans
  • Infusions, Intravenous
  • Pregnancy
  • Pregnancy Complications, Hematologic / drug therapy
  • Recombinant Proteins


  • Antithrombins
  • Recombinant Proteins