Nurses in health care today need to practice from an evidence base. There are many models to guide nurses in using the evidence in their practice; however, often nurses rely on their own mental processes to deliver care and do not rely on protocols or guidelines. The challenge often is not to teach the correct evidence-based practice guideline but to support the nurse to incorporate the guidelines into daily practice. Simulation is a method that can be used in an overall strategy to diffuse evidence-based practice guidelines at the point of care delivery.