Sexual Differentiation in Fission Yeast

Trends Genet. 1990 Nov;6(11):369-73. doi: 10.1016/0168-9525(90)90279-f.


The regulation of sexual reproduction in yeast constitutes the highest level of differentiation observed in these unicellular organisms. The various ramifications of this system involve DNA rearrangement, transcriptional control, post-translational modification (such as protein phosphorylation) and receptor/signal processing. A few basic similarities are common to both fission and budding yeasts. The wiring of the regulatory circuitry, however, varies considerably between these divergent yeast groups.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Conjugation, Genetic
  • Genes, Fungal
  • Meiosis
  • Protein Biosynthesis
  • Reproduction
  • Schizosaccharomyces / genetics*
  • Schizosaccharomyces / physiology
  • Transcription, Genetic