Rheumatoid arthritis

Aust Fam Physician. 2010 Sep;39(9):626-8.

Abstract

Background: Rheumatoid arthritis is a chronic disease that can cause irreversible joint damage and significant disability. With a prevalence of 1%, it has a considerable cost to the community. Diagnosis is based on a combination of clinical and laboratory features. Patients typically present with a symmetrical polyarthritis of the small joints of the hands and feet accompanied by early morning stiffness and, occasionally, constitutional symptoms.

Objective: This review discusses the role of the general practitioner in the diagnosis and early management of rheumatoid arthritis.

Discussion: It is increasingly recognised that there is a 'window of opportunity' within which disease modifying antirheumatic drug therapy should be commenced to arrest progressive disease and joint destruction. Methotrexate is usually the first line agent in the management of rheumatoid arthritis but simple analgesia and nonsteroidal anti-inflammatory drugs are also important for symptom control.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / diagnosis*
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / epidemiology
  • Arthritis, Rheumatoid / pathology
  • Australia / epidemiology
  • Biomarkers
  • Diagnosis, Differential
  • Fatty Acids, Omega-3 / therapeutic use
  • Humans
  • Practice Guidelines as Topic

Substances

  • Adrenal Cortex Hormones
  • Antirheumatic Agents
  • Biomarkers
  • Fatty Acids, Omega-3