Reversible conduction failure in pharyngeal-cervical-brachial variant of Guillain-Barré syndrome

Muscle Nerve. 2010 Oct;42(4):608-12. doi: 10.1002/mus.21801.


In two patients with the pharyngeal-cervical-brachial variant (PCB) of Guillain-Barré syndrome (GBS), low amplitude distal compound muscle action potentials and partial motor conduction blocks normalized without development of excessive temporal dispersion within 4 weeks. Sensory nerve action potentials significantly improved in amplitude or, when absent, rapidly became recordable at follow-up. Besides axonal degeneration, PCB is characterized by reversible conduction failure in both motor and sensory fibers and is in the continuous spectrum of axonal GBS subtypes.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials
  • Aged
  • Arm*
  • Axons
  • Follow-Up Studies
  • Guillain-Barre Syndrome / classification
  • Guillain-Barre Syndrome / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Motor Neurons
  • Muscle Weakness*
  • Muscle, Skeletal / physiopathology*
  • Neck Muscles / physiopathology*
  • Nerve Degeneration
  • Neural Conduction*
  • Sensory Receptor Cells
  • Shoulder*