Severe ocular reactions after neonatal ocular prophylaxis with gentamicin ophthalmic ointment

Pediatr Infect Dis J. 2011 Feb;30(2):175-6. doi: 10.1097/INF.0b013e3181f6c2e5.

Abstract

In this study, we report 4 infants who developed severe ocular reactions after neonatal ocular prophylaxis with gentamicin ophthalmic ointment during a period of erythromycin ophthalmic ointment shortage. In light of this experience, gentamicin ophthalmic ointment should not be used as an alternative for neonatal ocular prophylaxis.

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Antibiotic Prophylaxis / adverse effects*
  • Antibiotic Prophylaxis / methods
  • Gentamicins / administration & dosage
  • Gentamicins / adverse effects*
  • Humans
  • Infant, Newborn
  • Ointments / administration & dosage
  • Ointments / adverse effects*
  • Ophthalmia Neonatorum / prevention & control*

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Ointments