Polypoidal choroidal vasculopathy: recent advances in therapy

Curr Drug Targets. 2011 Feb;12(2):206-11. doi: 10.2174/138945011794182782.

Abstract

Polypoidal Choroidal Vasculopathy (PCV) is a condition characterized by chronic, multiple, recurrent serous and/or hemorrhagic detachments of the retinal pigment epithelium (RPE) and neurosensory retina. Although it has been described to more often affect Asians and individuals of pigmented races, PCV may also be present in white patients who present with the clinical appearance of age related macular degeneration (AMD). PCV and its treatment are discussed, including the use of combination therapy.

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Blindness / prevention & control
  • Choroid / blood supply
  • Choroid Diseases / diagnosis
  • Choroid Diseases / drug therapy*
  • Choroid Diseases / physiopathology
  • Choroid Diseases / therapy
  • Combined Modality Therapy
  • Humans
  • Laser Coagulation
  • Peripheral Vascular Diseases / diagnosis
  • Peripheral Vascular Diseases / drug therapy*
  • Peripheral Vascular Diseases / physiopathology
  • Peripheral Vascular Diseases / therapy
  • Photochemotherapy
  • Photosensitizing Agents / therapeutic use
  • Polyps / diagnosis
  • Polyps / drug therapy*
  • Polyps / physiopathology
  • Polyps / therapy
  • Porphyrins / therapeutic use
  • Retinal Detachment / etiology
  • Vascular Endothelial Growth Factors / antagonists & inhibitors
  • Verteporfin

Substances

  • Angiogenesis Inhibitors
  • Photosensitizing Agents
  • Porphyrins
  • Vascular Endothelial Growth Factors
  • Verteporfin