Facile fabrication of networked patterns and their superior application to realize the virus immobilized networked pattern circuit

Chem Commun (Camb). 2010 Dec 7;46(45):8609-11. doi: 10.1039/c0cc03323e. Epub 2010 Oct 4.

Abstract

A facile route to fabricate a protein-immobilized network pattern circuit for rapid and highly sensitive diagnosis was developed via the evaporation directed impromptu patterning method and selective avian influenza virus (AIV) immobilization. The response to the 10 fg mL(-1) anti-AI antibody demonstrates that this easy and simple circuit has about 1000 times higher sensitivity compared to those of conventional approaches.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biosensing Techniques / methods*
  • Birds / virology
  • Electricity*
  • Gold / chemistry
  • Immobilized Proteins / chemistry*
  • Influenza A Virus, H5N1 Subtype / isolation & purification
  • Influenza A Virus, H9N2 Subtype / isolation & purification
  • Influenza A virus / isolation & purification*
  • Influenza in Birds / diagnosis
  • Nanotubes, Carbon / chemistry
  • Peptide Fragments / chemistry
  • Viral Proteins / chemistry*
  • Volatilization

Substances

  • Immobilized Proteins
  • Nanotubes, Carbon
  • Peptide Fragments
  • Viral Proteins
  • Gold