Neosartorya fischeri var fischeri (Wehmer) Malloch and Cain 1972 (anamorph: Aspergillus fischerianus Samson and Gams 1985) as a cause of mycotic keratitis

Eur J Epidemiol. 1990 Dec;6(4):382-5. doi: 10.1007/BF00151712.


The first case of mycotic keratitis caused by Neosartorya fischeri var. fischeri the teleomorph of Aspergillus fischerianus, is described. The patient, a 62-year-old man, had no history of trauma to his infected left eye. The infection progressed despite treatment with ketoconazole and the eye had to be eviscerated. Histological studies revealed the presence of hyaline, septate mycelium in the eye tissue. Cultures gave rise to a thermotolerant mould that developed both its asexual and sexual forms. The isolate was identified on the basis of the morphologic features of its anamorphic and teleomorphic states. In the literature only seven other species of Aspergillus have been unequivocally reported as causing mycotic keratitis.

Publication types

  • Case Reports

MeSH terms

  • Aspergillosis* / drug therapy
  • Aspergillus / growth & development
  • Aspergillus / isolation & purification
  • Cornea / microbiology
  • Eye Enucleation
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / microbiology*
  • Humans
  • Keratitis / drug therapy
  • Keratitis / microbiology*
  • Ketoconazole / therapeutic use
  • Male
  • Middle Aged
  • Vitreous Body / microbiology


  • Ketoconazole