A cautionary tale of virus and disease

BMC Biol. 2010 Sep 27;8:124. doi: 10.1186/1741-7007-8-124.


The recent identification of the gammaretrovirus XMRV and a second gammaretrovirus of a different subtype in chronic fatigue syndrome has aroused much interest, not least among sufferers. However, it remains highly controversial whether the detection of these viruses represents true infection or laboratory artifacts.

MeSH terms

  • Animals
  • Fatigue Syndrome, Chronic / etiology*
  • Fatigue Syndrome, Chronic / virology*
  • Humans
  • Leukocytes, Mononuclear / virology
  • Mice
  • Neoplasms / virology*
  • Simian virus 40
  • Xenotropic murine leukemia virus-related virus*