Using Complementary and Alternative Medicines for Depression

J Clin Psychiatry. 2010 Sep;71(9):e24. doi: 10.4088/JCP.8157tx3c.


The use of complementary and alternative medicines (CAM) has increased among patients with psychiatric disorders over recent decades. Therefore, clinicians must inquire and be knowledgeable about the use of CAM therapies, not only to give their patients accurate and up-to-date information but also to know when to appropriately prescribe CAM therapies to patients. Of the available CAMs, omega-3 fatty acids, folate, SAM-e, and St John's wort are reviewed.

Publication types

  • Interactive Tutorial

MeSH terms

  • Antidepressive Agents / therapeutic use*
  • Complementary Therapies*
  • Depressive Disorder / therapy*
  • Fatty Acids, Omega-3 / therapeutic use
  • Folic Acid / therapeutic use
  • Humans
  • Hypericum
  • Phytotherapy
  • S-Adenosylmethionine / analogs & derivatives
  • S-Adenosylmethionine / therapeutic use


  • Antidepressive Agents
  • Fatty Acids, Omega-3
  • adenosyl-methionine 1,4-butanedisulfonate
  • S-Adenosylmethionine
  • Folic Acid