Mechanisms of sperm-egg interactions: between sugars and broken bonds

Sci Signal. 2010 Oct 5;3(142):pe35. doi: 10.1126/scisignal.3142pe35.

Abstract

A model of the early events of mammalian fertilization has emerged during the past 30 years. However, studies during the past decade have used newly available mouse models to readdress these processes. Here, we will consider these new data in light of the existing model and point to areas of reconciliation and of controversy.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Mice
  • Models, Biological*
  • Polysaccharides / metabolism*
  • Sperm-Ovum Interactions / physiology*

Substances

  • Polysaccharides