Childhood pineal parenchymal tumors: clinical and therapeutic aspects

Neurosurg Rev. 2010 Apr;34(2):191-6. doi: 10.1007/s10143-010-0287-0. Epub 2010 Oct 6.

Abstract

The aim of our study was to investigate the correlation of the clinical characteristic of pineal parenchymal tumors in children and adolescent with histopathological diagnosis and patient survival. Records of 27 patients with histologically diagnosed pineocytomas (n=16) and pineoblastoma (n=11) consecutively treated between 1991 and 2001 were reviewed retrospectively to identify factors predictive of aggressiveness. Among analyzed epidemiological, clinical, and radiological factors, we found that independent prognostic indicator in patients with childhood pineal parenchymal tumor was the extent of surgical resection.

MeSH terms

  • Adolescent
  • Cerebral Aqueduct / pathology
  • Chemotherapy, Adjuvant
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Contrast Media
  • Female
  • Humans
  • Hydrocephalus / complications
  • Hydrocephalus / surgery
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures
  • Pinealoma / epidemiology
  • Pinealoma / pathology*
  • Pinealoma / surgery*
  • Prognosis
  • Retrospective Studies
  • Survival Analysis
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ventriculoperitoneal Shunt
  • Ventriculostomy
  • Young Adult

Substances

  • Contrast Media