Measurement of substrate and inhibitor binding to microsomal cytochrome P-450 by optical-difference spectroscopy

Methods Enzymol. 1978:52:258-79. doi: 10.1016/s0076-6879(78)52029-6.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adrenal Medulla / enzymology
  • Animals
  • Cattle
  • Cytochrome P-450 Enzyme System / metabolism*
  • Electron Spin Resonance Spectroscopy / methods
  • Enzyme Induction / drug effects
  • Ligands
  • Microsomes / enzymology*
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology*
  • Phenobarbital / pharmacology
  • Pseudomonas / enzymology
  • Rats
  • Spectrophotometry / methods

Substances

  • Ligands
  • Cytochrome P-450 Enzyme System
  • Phenobarbital