[Chronic venous insufficiency in postthrombotic syndrome and varicose veins]

Praxis (Bern 1994). 2010 Oct 6;99(20):1195-202. doi: 10.1024/1661-8157/a000262.
[Article in German]


Venous disorders have a high prevalence and require approximately 1% of health budgets of industrialized countries. The postthrombotic syndrome (PTS) is defined by subjective symptoms and morphologic trophical skin changes following deep venous thrombosis. Prevention of venous thromboembolism in risk situations, easy availability of diagnostic tools (D-dimers, colour-coded duplex sonography) and early detection of deep venous thrombosis, as well as immediate therapeutic anticoagulation along with leg compression during the acute phase and over a two year period of time significantly reduce the incidence of PTS. Chronic venous insufficiency (CVI) includes trophical skin and soft tissue pathologies of the lower leg due to venous hypertension in the distal venous system of the lower extremity. Roughly, two main causes can be distinguished. (A) Deep venous insufficiency (A1 in postthrombotic syndrome; A2 in primary deep venous insufficiency) and (B) superficial venous reflux, usually varicose veins. Compression therapy, surgical ablation of superficial venous reflux, and tangential ablation with split skin graft (shave treatment) of refractory venous ulcers are the mainstays in the treatment of CVI.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Humans
  • Postthrombotic Syndrome / diagnosis*
  • Postthrombotic Syndrome / etiology
  • Postthrombotic Syndrome / therapy
  • Risk Factors
  • Skin Transplantation / methods
  • Stockings, Compression
  • Surgical Mesh
  • Thrombophlebitis / diagnosis
  • Thrombophlebitis / etiology
  • Thrombophlebitis / therapy
  • Varicose Ulcer / diagnosis*
  • Varicose Ulcer / etiology
  • Varicose Ulcer / therapy
  • Varicose Veins / diagnosis*
  • Varicose Veins / etiology
  • Varicose Veins / therapy
  • Venous Insufficiency / diagnosis*
  • Venous Insufficiency / etiology
  • Venous Insufficiency / therapy