FliZ induces a kinetic switch in flagellar gene expression

J Bacteriol. 2010 Dec;192(24):6477-81. doi: 10.1128/JB.00751-10. Epub 2010 Oct 8.

Abstract

FliZ is an activator of class 2 flagellar gene expression in Salmonella enterica. To understand its role in flagellar assembly, we investigated how FliZ affects gene expression dynamics. We demonstrate that FliZ participates in a positive-feedback loop that induces a kinetic switch in class 2 gene expression.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Flagella / genetics
  • Flagella / metabolism*
  • Gene Expression Regulation, Bacterial / physiology*
  • Kinetics
  • Salmonella enterica / genetics*
  • Salmonella enterica / metabolism*
  • Time Factors

Substances

  • Bacterial Proteins