Atypical presentation of atypical amyloid

Nephrol Dial Transplant. 2011 Jan;26(1):373-6. doi: 10.1093/ndt/gfq638. Epub 2010 Oct 12.


Amyloidosis is a group of diseases categorized by precipitation of a group of protein aggregates (amyloid) in tissues, including the kidney, and proteinuria is usually the commonest, though not exclusive, hallmark of clinical presentation. AL and AA are the most commonly recognized forms of amyloidosis involving the kidney, but other forms have been described. We present a case of renal amyloidosis due to a novel amyloidogenic protein, leucocyte cell-derived chemotaxin 2, without proteinuria at presentation or on subsequent follow-up.

Publication types

  • Case Reports

MeSH terms

  • Amyloidosis / complications*
  • Amyloidosis / metabolism
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Intercellular Signaling Peptides and Proteins / metabolism
  • Kidney Diseases / etiology*
  • Kidney Diseases / metabolism
  • Kidney Diseases / pathology
  • Middle Aged
  • Proteinuria / etiology*
  • Proteinuria / metabolism
  • Proteinuria / pathology
  • Serum Amyloid A Protein / metabolism*


  • Intercellular Signaling Peptides and Proteins
  • LECT2 protein, human
  • Serum Amyloid A Protein