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, 3 (143), pt1

Hormone Resistance at the Clinical Level

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Hormone Resistance at the Clinical Level

Ze'ev Hochberg. Sci Signal.

Abstract

This presentation introduces clinical aspects of hormone resistance through a number of case studies that illustrate how molecular defects at various steps in hormone production, signaling, or responsiveness can produce disease in humans. The presentation also shows how careful phenotyping of such patients has triggered decades of translational research.

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