Adjuvant effect of cavinton in the treatment of climacteric symptoms

Ther Hung. 1990;38(4):170-3.


A comparative study has been performed in 40 climacteric, postmenopausal women. In the course of the examinations the results of two therapeutic methods were compared: hormone substitution therapy and combined hormone substitution and Cavinton adjuvant therapy. The improvement in the climacteric symptoms was measured by Kupperman's index and the results were statistically analysed. According to the results Cavinton significantly improves the changes in the symptoms to be obtained with oestrogen substitution. On the basis of the observations the author recommends the combination therapy. Cavinton did not cause side-effects which would have influenced the long-term use of the drug.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Climacteric / drug effects*
  • Drug Evaluation
  • Estrogen Replacement Therapy
  • Female
  • Humans
  • Middle Aged
  • Vasodilator Agents / therapeutic use*
  • Vinca Alkaloids / therapeutic use*


  • Vasodilator Agents
  • Vinca Alkaloids
  • vinpocetine