[Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia]

Minerva Urol Nefrol. 2010 Sep;62(3):213-8.
[Article in Italian]


Aim: Among the factors contributing to male infertility, asthenospermia constitutes both a health and a social problem frequently associated with alterations in sexual function. Studies have shown that acetyl carnitine and L-arginine improve sperm motility and that ginseng enhances libido and sexual performance. This study examined the effect of treatment with carnitine, acetyl carnitine, L-arginine and ginseng in men with idiopathic asthenospermia and altered sexual function.

Methods: The study population was 180 patients with asthenospermia randomly assigned to two groups: group A (90 men) received treatment and group B (90 men) did not. The sperm count was 16.6 ± 3.2 x 10⁶/mL and the total sperm motility was 26.5 ± 3.4%.

Results and conclusion: Sexual satisfaction was measured using the sexual satisfaction index (SSI). At the end of therapy, a significant improvement was observed in progressive sperm motility on spermiogram evaluation and in SSI scores in the treatment group.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Acetylcarnitine / therapeutic use
  • Adult
  • Arginine / therapeutic use*
  • Asthenozoospermia / drug therapy*
  • Carnitine / therapeutic use*
  • Double-Blind Method
  • Humans
  • Male
  • Middle Aged
  • Panax*
  • Phytotherapy*
  • Semen Analysis
  • Sexuality / drug effects*
  • Sperm Motility / drug effects*
  • Vitamin B Complex / therapeutic use


  • Vitamin B Complex
  • Acetylcarnitine
  • Arginine
  • Carnitine