Intergenic suppression of spoO phenotypes by the Bacillus subtilis mutation rvtA

R A Sharrock; S Rubinstein; M Chan; T Leighton

doi:10.1007/BF00383525

Intergenic suppression of spoO phenotypes by the Bacillus subtilis mutation rvtA

Mol Gen Genet. 1984;194(1-2):260-4. doi: 10.1007/BF00383525.

Authors

R A Sharrock¹, S Rubinstein, M Chan, T Leighton

Affiliation

¹ Department of Microbiology and Immunology, University of California, Berkeley, California 94720, USA

PMID: 20941882
DOI: 10.1007/BF00383525

Abstract

A collection of intergenic suppressors of the Bacillus subtilis spoOF221 mutation has been isolated. One of these suppressors, rvtA, has been mapped between lys-1and aroD. The rvtA suppressor restores spoOF sporulation to wild type levels and substantially improves the sporulation efficiencies of spoOB and spoOE strains. The rvtA gene does not affect the Spo phenotype of spoOH, spoOJ or spoOK mutants. The rvtA gene also prevents the induction by aliphatic alcohols of SpoO phenocopies in wild type B. subtilis cells.

MeSH terms

Bacillus subtilis / genetics*
Bacillus subtilis / metabolism*
Bacterial Proteins* / genetics
Bacterial Proteins* / metabolism
Chromosome Mapping
DNA, Bacterial / genetics*
DNA, Intergenic / genetics*
Mutation / genetics*
Phenotype*
Spores, Bacterial / growth & development
Suppression, Genetic / genetics

Substances

Bacterial Proteins
DNA, Bacterial
DNA, Intergenic