Epigenomics reveals a functional genome anatomy and a new approach to common disease

Nat Biotechnol. 2010 Oct;28(10):1049-52. doi: 10.1038/nbt1010-1049.

Abstract

Epigenomics provides the context for understanding the function of genome sequence, analogous to the functional anatomy of the human body provided by Vesalius a half-millennium ago. Much of the seemingly inconclusive genetic data related to common diseases could therefore become meaningful in an epigenomic context.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Disease / genetics*
  • Epigenesis, Genetic
  • Epigenomics*
  • Genome, Human / genetics*
  • Humans
  • Neoplasms / genetics
  • Peer Review, Research
  • Periodicals as Topic / statistics & numerical data