Identification of a new HLA-A*02 allele, HLA-A*02:230, using polymerase chain reaction sequence-based typing in a Chinese individual

F-M Zhu; Y-M He; H-J Lv; L-X Yan

doi:10.1111/j.1399-0039.2010.01573.x

Identification of a new HLA-A02 allele, HLA-A02:230, using polymerase chain reaction sequence-based typing in a Chinese individual

Tissue Antigens. 2011 Feb;77(2):150-1. doi: 10.1111/j.1399-0039.2010.01573.x. Epub 2010 Oct 12.

Authors

F-M Zhu¹, Y-M He, H-J Lv, L-X Yan

Affiliation

¹ HLA typing laboratory, Blood Center of Zhejiang Province, Hangzhou, Zhejiang Province, China.

PMID: 20946196
DOI: 10.1111/j.1399-0039.2010.01573.x

Abstract

Nucleotide sequence of HLA-A*02:230 allele was different from that of HLA-A*02:03:01 by a single nucleotide substitution at codon 139 (GCA > ACA), resulting in one amino acid change (Ala to Thr).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Amino Acid Substitution
Asian People / genetics*
Base Sequence
Exons / genetics
HLA-A Antigens / genetics*
HLA-A2 Antigen
Humans
Molecular Sequence Data
Polymerase Chain Reaction*
Sequence Homology, Nucleic Acid

Substances

HLA-A Antigens
HLA-A*02 antigen
HLA-A2 Antigen