Identification of a new HLA-A*02 allele, HLA-A*02:230, using polymerase chain reaction sequence-based typing in a Chinese individual

Tissue Antigens. 2011 Feb;77(2):150-1. doi: 10.1111/j.1399-0039.2010.01573.x. Epub 2010 Oct 12.

Abstract

Nucleotide sequence of HLA-A*02:230 allele was different from that of HLA-A*02:03:01 by a single nucleotide substitution at codon 139 (GCA > ACA), resulting in one amino acid change (Ala to Thr).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Amino Acid Substitution
  • Asians / genetics*
  • Base Sequence
  • Exons / genetics
  • HLA-A Antigens / genetics*
  • HLA-A2 Antigen
  • Humans
  • Molecular Sequence Data
  • Polymerase Chain Reaction*
  • Sequence Homology, Nucleic Acid

Substances

  • HLA-A Antigens
  • HLA-A*02 antigen
  • HLA-A2 Antigen