The SMARTCyp cytochrome P450 metabolism prediction server

Patrik Rydberg; David E Gloriam; Lars Olsen

doi:10.1093/bioinformatics/btq584

The SMARTCyp cytochrome P450 metabolism prediction server

Bioinformatics. 2010 Dec 1;26(23):2988-9. doi: 10.1093/bioinformatics/btq584. Epub 2010 Oct 14.

Authors

Patrik Rydberg¹, David E Gloriam, Lars Olsen

Affiliation

¹ Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

PMID: 20947523
DOI: 10.1093/bioinformatics/btq584

Abstract

Summary: The SMARTCyp server is the first web application for site of metabolism prediction of cytochrome P450-mediated drug metabolism.

Availability: The SMARTCyp server is freely available for use on the web at www.farma.ku.dk/smartcyp where the SMARTCyp Java program and source code is also available for download.

Contact: smartcyp@farma.ku.dk; lo@farma.ku.dk

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computational Biology
Cytochrome P-450 Enzyme System / metabolism*
Inactivation, Metabolic
Software*
User-Computer Interface

Substances

Cytochrome P-450 Enzyme System