Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 2

Management of Helicobacter Pylori

Management of Helicobacter Pylori

Seiji Shiota et al. F1000 Med Rep.


Meta-analysis has shown that successful Helicobacter pylori eradication therapy improved atrophic gastritis and intestinal metaplasia. Moreover, successful eradication therapy against atrophic gastritis has led to the suppression of the incidence of metachronous gastric cancer. Thus, the Japanese Society for Helicobacter Research concluded that all 'H. pylori-infected persons' should be considered for eradication therapy, irrespective of any background diseases. Successful eradication can prevent transmission of this bacterium, and recent publications show that curing H. pylori infection seems to reduce the risk of gastric cancer.

Similar articles

See all similar articles

Cited by 5 PubMed Central articles


    1. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. Yamada T, Searle JG, Ahnen D, Aipers DH, Greenberg HB, Gray M, Joscelyn KB, Kauffman G, Podolsky DK, Ray WA, Schaberg D, Silverstein FE, Sivak MV, Jr, Williams AL, Yolken R, Blaser MJ, Borsch G, Correa P, Czinn SJ, Forman D, Graham DY, Isenberg JL, Jensen DM, Marshall BJ, Parsonnet J, Peterson WL, Sipponen P, Smoot DT, Soil AH, et al. Helicobacter pylori in peptic ulcer disease. JAMA. 1994;272:65–9. - PubMed
    1. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, Taniyama K, Sasaki N, Schlemper R. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med. 2001;345:784–9. doi: 10.1056/NEJMoa001999. - DOI - PubMed
    1. Wotherspoon A, Ortiz-Hidalgo C, Falzon M, Isaacson P. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet. 1991;338:1175–6. doi: 10.1016/0140-6736(91)92035-Z. - DOI - PubMed
    1. Malfertheiner P, Megraud F, O’Morain C, Bazzoli F, El-Omar E, Graham D, Hunt R, Rokkas T, Vakil N, Kuipers E. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut. 2007;56:772–81. doi: 10.1136/gut.2006.101634. - DOI - PMC - PubMed
    2. Changes Clinical Practice

      f1000 Factor 6.0 Must Read

      Evaluated by Steven Moss 23 Jul 2007

    1. Chey W, Wong B. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol. 2007;102:1808–25. doi: 10.1111/j.1572-0241.2007.01393.x. - DOI - PubMed

LinkOut - more resources