Easiness of use and validity testing of VS-SENSE device for detection of abnormal vaginal flora and bacterial vaginosis

Infect Dis Obstet Gynecol. 2010:2010:504972. doi: 10.1155/2010/504972. Epub 2010 Oct 7.


Accessing vaginal pH is fundamental during gynaecological visit for the detection of abnormal vaginal flora (AVF), but use of pH strips may be time-consuming and difficult to interpret. The aim of this study was to evaluate the VS-SENSE test (Common Sense Ltd, Caesarea, Israel) as a tool for the diagnosis of AVF and its correlation with abnormal pH and bacterial vaginosis (BV). The study population consisted of 45 women with vaginal pH ≥ 4.5 and 45 women with normal pH. Vaginal samples were evaluated by VS-SENSE test, microscopy and microbiologic cultures. Comparing with pH strips results, VS-SENSE test specificity was 97.8% and sensitivity of 91%. All severe cases of BV and aerobic vaginitis (AV) were detected by the test. Only one case with normal pH had an unclear result. Concluding, VS-SENSE test is easy to perform, and it correlates with increased pH, AVF, and the severe cases of BV and AV.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Azo Compounds
  • Bacteria / isolation & purification
  • Bacteriological Techniques / methods*
  • Chi-Square Distribution
  • Color
  • Female
  • Humans
  • Hydrogen-Ion Concentration
  • Microscopy
  • Middle Aged
  • Predictive Value of Tests
  • Reproducibility of Results
  • Vagina / microbiology*
  • Vaginosis, Bacterial / diagnosis*


  • Azo Compounds
  • nitrazine yellow