Stanford University network for diagnosis of retinopathy of prematurity (SUNDROP): 36-month experience with telemedicine screening

Ophthalmic Surg Lasers Imaging. Jan-Feb 2011;42(1):12-9. doi: 10.3928/15428877-20100929-08. Epub 2010 Sep 29.


Background and objective: to report the 36-month experience of the Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP) telemedicine initiative.

Patients and methods: retrospective analysis of the SUNDROP archival data between December 1, 2005, and November 30, 2008, to evaluate this diagnostic technology for retinopathy of prematurity (ROP) screening. A total of 230 consecutively enrolled infants meeting ROP examination criteria were screened with the Ret-Cam II (Clarity Medical Systems, Pleasanton, CA) and evaluated by the SUNDROP reading center at Stanford University. Outcomes included referral-warranted ROP, treatment-warranted ROP, and anatomic outcomes.

Results: in the initial 36-month period, the SUNDROP telemedicine initiative did not miss any treatment-warranted ROP. A total of 230 infants (460 eyes) were imaged, resulting in 1,059 examinations and 10,921 unique images. Ten infants were identified with referral-warranted ROP: nine underwent laser photocoagulation and one regressed spontaneously. The sensitivity was 100% with a specificity of 99.5%. No patient progressed to retinal detachment or other adverse outcomes.

Conclusion: the SUNDROP telemedicine screening initiative for ROP has demonstrated high reliability for identification of treatment-warranted disease. All cases of treatment-warranted disease were captured. There were no adverse outcomes.

MeSH terms

  • Academic Medical Centers / organization & administration
  • Birth Weight
  • California
  • Diagnostic Techniques, Ophthalmological / standards*
  • False Negative Reactions
  • Gestational Age
  • Humans
  • Image Interpretation, Computer-Assisted
  • Infant, Newborn
  • Neonatal Nursing / methods*
  • Photography / standards*
  • Predictive Value of Tests
  • Retinopathy of Prematurity / diagnosis*
  • Retrospective Studies
  • Sensitivity and Specificity
  • Telemedicine / organization & administration
  • Telemedicine / standards*